The agreement came after Choi Yang-hee -- minister of science, ICT and future planning -- held the talks earlier with John Holdren, senior adviser to President Barack Obama on science and technology issues in Seoul.
It marked the 9th session of the joint committee meeting on science and technology cooperation between the two sides.
The biennial forum, launched in 1993, represents the allies' determination to strengthen their ties in the field.
The main agenda items included issues of mutual concern like innovation, cybersecurity, climate change, contagious diseases and research & development, according to the ministry.
It said South Korea and the U.S. have expanded the scope of discussions to artificial intelligence and ways to deal with global challenges on top of traditional cooperation in such fields as nano- and biotechnology.
"South Korea, especially, actively proposed ways for collaborating on software education for the future generation," it said, adding the talks have paved the way for closer cooperation on the sector. It did not provide details.
"The U.S. side asked for South Korea's universities and companies to participate," the ministry said.
On cybersecurity, the two countries agreed on the need for closer cooperation through joint research and the exchange of related manpower.
The two sides also had working-group meetings on five sectors: nanotechnology, health, ICT R&D, robotics and wildlife, according to the ministry. (Yonhap)