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2012-08-15 17:04

Blood type might be a clue to heart disease risk

Here's another reason to know your blood type ― it might be a clue to your risk of heart disease.

People who have blood types A, B, or AB have a slightly higher risk of heart disease compared to those with type O, the most common kind, according to research released Tuesday.

Those who know they are at higher risk may be more motivated to make changes to lower their chances of heart disease, said Dr. Lu Qi, senior author of the study from Harvard School of Public Health in Boston.

``We cannot change blood type but we can change lifestyle,'' said Qi, who led a study released last year that showed blood type may affect stroke risk.

The new study involved about 90,000 men and women in two observational health studies that cover more than 20 years. Combined, 4,070 people developed heart disease. The researchers considered age and other factors like diet, drinking, family history of heart attacks that could contribute to heart disease.

The increased risk for type A was 8 percent; type B, 11 percent; and type AB, 20 percent.

While the study did not examine how blood type may affect heart disease risk, it noted that research has shown some characteristics of different types may be a factor. For instance, some research suggests that blood types might affect cholesterol levels or the risk of developing blood clots.

The findings were published in the American Heart Association journal Arteriosclerosis, Thrombosis and Vascular Biology.

A doctor not involved in the study cautioned that the increased risk for non-O blood types is modest, and that other risk factors like smoking have a bigger impact.

``Most of things that are this modest, most of the time they don't meaningfully change how you'd think about your risk overall,'' said Dr. Amit Khera, director of the Preventive Cardiology Program at the University of Texas Southwestern Medical Center in Dallas.

``This shouldn't cause much alarm for most of the population,'' he added.

No matter what blood type, Harvard's Qi said everyone should pay attention to risk factors they can change, including smoking, weight, high cholesterol, high blood pressure and a sedentary lifestyle.

Type O is the most common blood type, followed by A, B and AB. About 45 percent of whites, 51 percent of blacks, 57 percent of Hispanics and 40 percent of Asians have blood type O, according to the American Red Cross.

Type A: 40 percent of whites, 26 percent of blacks, 31 percent of Hispanics and 28 percent of Asians.

Type B: 11 percent of whites, 19 percent of blacks, 10 percent of Hispanics and 25 percent of Asians.

Type AB: 4 percent of white and blacks, 2 percent of Hispanics and 7 percent of Asians. (AP)




관련 한글기사


심장병위험: AB형 가장 높고, O형 낮아

미국 하버드 대학 보건대학원의 치뤼(Lu Qi) 박사는 심장병 위험은 혈액형이 O형인 사람이 가장 낮고 AB형인 사람이 가장 높다는 연구결과를 발표했다고 NBC 인터넷판과 헬스데이 뉴스가 14일 보도했다.

치 박사는 남녀 9만명(30-75세)을 대상으로 24-26년 동안 실시된 조사 자료를 분석한 결과 혈액형에 따른 심장병 위험은 0형이 가장 낮고 A형은 0형에 비해 5%, B형은 11%, AB형은 23% 높은 것으로 나타났다고 밝혔다.

이 결과는 식습관, 연령, 체중, 성별, 흡연, 폐경, 병력 등 일반적인 심장병 위험요인들을 고려한 것이다.

조사대상자들은 대부분 백인이기 때문에 이 결과가 다른 인종에도 적용될 수 있을지는 알 수 없다.

미국심장학회(AHA) 대변인이자 심장병 전문의인 리처드 스테인 박사는 "놀라운 결과"라면서 확인을 위해 앞으로 연구가 더 필요하겠지만 환자의 심장병 위험을 평가할 때 의사가 고려해야 할 위험인자에 혈액형을 추가해야 하는 것 아닌지 모르겠다고 논평했다.

혈액형이 심장병 위험과 연관이 있는 이유는 정확히 알 수 없으나 O형 혈액은 혈액 흐름에 도움을 주고 혈전을 막아주는 인자를 지니고 있는지 모른다고 치 박사는 말했다.

로스앤젤레스 캘리포니아 대학 의과대학 심장병전문의 그레그 포나로 박사는 혈액형에 따라 콜레스테롤과 염증 또는 면역반응이 다를 수 있다고 설명했다.

이 연구결과는 의학전문지 '동맥경화-혈전-혈관생물학(Arteriosclerosis, Thrombosis and Vascular Biology)' 최신호(8월14일자)에 발표됐다. (연합뉴스)


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