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2012-01-31 18:41

Men could blast balls with ultrasonic waves to prevent pregnancy



What if the male version of the birth control pill wasn't a pill at all? Scientists from the University of North Carolina say a non-oral form of male contraception is on the horizon, news reports said Monday.

According to researchers, all it takes to be effective is a couple blasts of high frequency sound waves...delivered straight to the testicles.

Using ultrasound equipment typically used for physical therapy, a team of researchers led by UNC's James Tsuruta showed that exposing the testes of rats to two 15-minute "doses" of ultrasonic radiation could reduce sperm counts in the rats to levels that, in humans, would result in infertility, io9.com said.

If the effects prove reversible, and the treatment is deemed safe, ultrasonic contraception could soon become a common form of male birth control.

But would anybody actually use it? After all, having blasts of high-frequency sound waves propagate throughout your nether regions sounds pretty, well, intimidating; but preliminary human studies show that the treatment isn't painful at all.

Plus, when you consider the benefits of sound waves over an orally administered pill, ultrasonic ball-blasts actually start to sound pretty attractive.

For one thing, it would be cheap; the equipment used to deliver the doses is already ubiquitous in sports medicine and physical therapy clinics. Plus, there'd be no expensive drugs to synthesize, which also translates to cheaper treatment.

You also wouldn't have to remember to take a daily pill. When Tsuruta first received funding for his team's research from the Bill and Melinda Gates Foundation in 2010, he estimated that doses of ultrasound could be used to provide men with six months of reliable contraception. Of course, that was almost two years ago ― before he'd had a chance to see the results of his tests on rats ― but even if it only lasted two or three months, a few short visits a year would probably still be preferable to a daily pill for a lot of people.

But plenty of questions about the efficacy and safety of ultrasonic contraception remain, namely: how long does a single treatment last, are the treatment's effects reversible, do multiple treatments cause any long-term damage, and do the ultrasonic doses have any negative effects on babies themselves?

"It's a nice idea, but a lot more work is needed," said University of Sheffield's Allan Pacey in an interview with BBC News, claiming it was likely that sperm production would recover, but that "sperm might be damaged and any baby might be damaged," as well.

"The last thing we want is a lingering damage to sperm," he said. A provisional version of the researchers' findings are published in Reproductive Biology and Endocrinology.




관련 한글 기사


초음파로 남성피임 가능

고환에 초음파를 발사하는 방법으로 남성피임이 가능하다는 연구결과가 나왔다.

미국 노스캐롤라이나 대학 의과대학의 소아과전문의 제임스 추루타(James Tsuruta) 박사는 고환 주위에 초음파를 발사하면 정자의 생산을 중단시킬 수 있다고 밝힌 것으로 영국의 BBC방송 인터넷판과 메디컬 뉴스 투데이가 30일(현지시간) 보도했다.

추루타 박사는 쥐의 고환주위에 회전고주파(3MHz) 초음파를 15분씩 두 차례 발사한 결과 고환의 정자를 만드는 생식세포와 정자 수가 크게 줄어들었다고 혔다.

초음파는 이틀 간격으로 발사했을 때 정자 수가 가장 많이 줄었다.

이 실험에는 초음파 변환기와 피부 사이의 전도성을 높이기 위해 식염수가 사용되었고 쥐의 고환은 온도를 섭씨 37도로 높였다.

쥐는 정자 수가 밀리미터 당 1천만 마리 이하로 줄어들었다. 사람의 경우 정자가 밀리미터 당 1천500만 마리 이하이면 준불임(sub-fertile)으로 간주된다. 남성은 95%가 한 번 사정에 3천900만 마리 이상의 정자를 방출한다.

이 결과는 초음파가 남성피임 수단이 될 수 있음을 보여주는 것이다.

그러나 피임효과가 얼마나 오래 지속되는지, 초음파를 되풀이 사용해도 안전한 것인지, 사용 후에는 정자 수가 회복되는지, 장기간 사용하면 정자에 손상이 발생하는 것은 아닌지 등을 확인하기 위해 앞으로 연구가 더 필요하다고 추루타 박사는 말했다.

이 연구결과는 '생식생물학-내분비학(Reproductive Biology and Endocrinology)' 최신호에 실렸다. (연합뉴스)


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